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SMILES: Cc1c(F)cccc1[C@]1(CC[C@H](C1)c1ccccc1)C(=O)NO

InChI Key: InChIKey=JYKNQHQPUVIRAZ-DNVCBOLYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344298   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 4


(Homo sapiens (Human))		BDBM344298
PNG
((1R*,3R*)-1-(3-Fluoro-2- methylphenyl)-N-hydroxy- ...)
Show SMILES Cc1c(F)cccc1[C@]1(CC[C@H](C1)c1ccccc1)C(=O)NO |r|
Show InChI InChI=1S/C19H20FNO2/c1-13-16(8-5-9-17(13)20)19(18(22)21-23)11-10-15(12-19)14-6-3-2-4-7-14/h2-9,15,23H,10-12H2,1H3,(H,21,22)/t15-,19-/m1/s1
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US Patent
n/an/a 50n/an/an/an/an/an/a



CHDI Foundation, Inc.

US Patent


Assay Description
The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...

US Patent US9783488 (2017)


BindingDB Entry DOI: 10.7270/Q2JH3P96
More data for this
Ligand-Target Pair