BDBM34524 2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]-4,6-dimethyl-isothiazolo[5,4-b]pyridin-3-one::4,6-dimethyl-2-[2-[3-methyl-4-(3-methylphenyl)-1-piperazinyl]-2-oxoethyl]-3-isothiazolo[5,4-b]pyridinone::4,6-dimethyl-2-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-[1,2]thiazolo[5,4-b]pyridin-3-one::4,6-dimethyl-2-[2-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]-2-oxoethyl]-[1,2]thiazolo[5,4-b]pyridin-3-one::MLS000118900::SMR000095840::cid_5309798

SMILES: CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O

InChI Key: InChIKey=PITXGJWJCXVBHV-UHFFFAOYSA-N

Data: 3 KI  3 IC50  10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 34524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QR4VJR
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q26T0K2P
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2G73C4V
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PZ578V
					More data for this Ligand-Target Pair
large T antigen (Simian virus 40)	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Specialized Biocontainment Screening Center Curated by PubChem BioAssay					Assay Description A biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to identify compounds that inhibit the ATPase activity of Tag Southern Re...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M61HQ8
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CF9NJZ
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2416VG3
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VH5M8G
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M043TQ
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BG2MFK
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.28E+3	n/a	n/a	n/a	n/a	8.0	23
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay					Assay Description A fluorescence resonance energy transfer assay is developed in 96-well and 384-well microplate formats with robotic manipulation to enable high-throu...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2H70D5W
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM34524 (2-[2-keto-2-[3-methyl-4-(m-tolyl)piperazino]ethyl]...) Show SMILES CC1CN(CCN1c1cccc(C)c1)C(=O)Cn1sc2nc(C)cc(C)c2c1=O Show InChI InChI=1S/C22H26N4O2S/c1-14-6-5-7-18(10-14)25-9-8-24(12-17(25)4)19(27)13-26-22(28)20-15(2)11-16(3)23-21(20)29-26/h5-7,10-11,17H,8-9,12-13H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair