Found 31 hits for monomerid = 34572 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| DrugBank Article PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Dublin
Curated by ChEMBL
| Assay Description Binding affinity to alpha2 adrenoceptor in human cortical membrane |
J Med Chem 52: 601-9 (2009)
Article DOI: 10.1021/jm800838r BindingDB Entry DOI: 10.7270/Q26M39MM |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
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| DrugBank
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity for Alpha-2 adrenergic receptor of CHO-C10 membrane preparation |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6F1V |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
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| DrugBank
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity towards Alpha-2 adrenergic receptor of HT-29 cells |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2V1270C |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | UniProtKB/SwissProt
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| Article PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells |
J Med Chem 40: 18-23 (1997)
Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST |
More data for this Ligand-Target Pair | |
adrenergic Alpha2
(OPOSSUM) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt
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| PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 244: 571-8 (1988)
BindingDB Entry DOI: 10.7270/Q25H7DS8 |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt
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| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat using [3H]rauwolscine as radioligand |
J Med Chem 28: 1398-404 (1985)
BindingDB Entry DOI: 10.7270/Q2H41TM1 |
More data for this Ligand-Target Pair | |
ADRA2A
(MOUSE) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | Reactome pathway
UniProtKB/TrEMBL
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| Article PubMed
| 43.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Bioscience
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 1035-43 (1998)
Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01 |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of rauwolscine from human Alpha-2C adrenergic receptor expressed in CHO cells |
J Med Chem 40: 18-23 (1997)
Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(NEONATAL RAT) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
Reactome pathway KEGG
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| Article PubMed
| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of rauwolscine from rat Alpha-2B adrenergic receptor expressed in CHO cells |
J Med Chem 40: 18-23 (1997)
Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
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| | 83 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity for human Alpha-2C adrenergic receptor from cultured LM(tk-) cells using [3H]- prazosin |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2DV1N3J |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | UniProtKB/SwissProt
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| Article PubMed
| 214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Bioscience
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 1035-43 (1998)
Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01 |
More data for this Ligand-Target Pair | |
adrenergic Alpha2
(PIG) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | Reactome pathway KEGG
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| PubMed
| 479 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 294: 539-47 (2000)
BindingDB Entry DOI: 10.7270/Q2TM78NR |
More data for this Ligand-Target Pair | |
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity against alpha-1 adrenergic receptor in rat using [3H]prazosin as radioligand |
J Med Chem 28: 1398-404 (1985)
BindingDB Entry DOI: 10.7270/Q2H41TM1 |
More data for this Ligand-Target Pair | |
Alpha-2B adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt
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| Article PubMed
| 955 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Bioscience
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 1035-43 (1998)
Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01 |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-1
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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| | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity towards Alpha-1 adrenergic receptor of human brain |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2V1270C |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-1
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | MMDB
KEGG
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| | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity for Alpha-1 adrenergic receptor of human cerebral cortex membrane |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6F1V |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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| Article PubMed
| 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Bioscience
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 1035-43 (1998)
Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01 |
More data for this Ligand-Target Pair | |
Alpha-1A adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
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| | 2.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity for human Alpha-1A adrenergic receptor from cultured LM(tk-) cells using [3H]-prazosin |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2DV1N3J |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
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| DrugBank Article PubMed
| n/a | n/a | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a |
University of Dublin
Curated by ChEMBL
| Assay Description Agonist activity at alpha2 adrenoceptor in human cortical membrane after 2 hrs by [35S]GTPgammaS binding assay |
J Med Chem 52: 601-9 (2009)
Article DOI: 10.1021/jm800838r BindingDB Entry DOI: 10.7270/Q26M39MM |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
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| DrugBank Article PubMed
| n/a | n/a | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a |
University of Dublin
Curated by ChEMBL
| Assay Description Agonist activity at human brain adrenergic alpha2 receptor by [35S]GTPgammaS binding assay |
J Med Chem 50: 4516-27 (2007)
Article DOI: 10.1021/jm070229q BindingDB Entry DOI: 10.7270/Q2571FSN |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
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| DrugBank PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of [3H]p-aminoclonidine (PAC) binding to alpha-2 adrenergic receptor of purified human platelet plasma membranes |
J Med Chem 30: 1241-4 (1987)
BindingDB Entry DOI: 10.7270/Q2JM2CWR |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
KEGG
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| DrugBank
| n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of Alpha-2 adrenergic receptor induced contractile response of rabbit vas deferens |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22J6F1V |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt
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| PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity against Alpha-2 adrenergic receptor is the ability to inhibit the specific [3H]clonidine binding (0.4 nM) to rat isolated brain memb... |
J Med Chem 27: 495-503 (1984)
BindingDB Entry DOI: 10.7270/Q24B31WH |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | UniProtKB/SwissProt
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| | n/a | n/a | n/a | n/a | 0.617 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Alpha-2A adrenergic receptor agonistic potency as inhibition of forskolin-stimulated synthesis of cyclic adenosine monophosphate |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2DV1N3J |
More data for this Ligand-Target Pair | |
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
Similars
| PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Binding affinity against alpha-1 adrenergic receptor is the ability to inhibit the specific [3H]prazosin binding (0.2 nM) to rat isolated brain membr... |
J Med Chem 27: 495-503 (1984)
BindingDB Entry DOI: 10.7270/Q24B31WH |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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| | n/a | n/a | n/a | n/a | 9.5 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Alpha-2C adrenergic receptor agonistic potency as inhibition of forskolin-stimulated cyclic adenosine monophosphate synthesis |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2DV1N3J |
More data for this Ligand-Target Pair | |
Adrenergic receptor alpha-2
(NEONATAL RAT) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | n/a | n/a | 55 | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals
Curated by ChEMBL
| Assay Description Effective Concentration at Alpha-2B adrenergic receptor from CHO-RNG cells |
J Med Chem 40: 18-23 (1997)
Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST |
More data for this Ligand-Target Pair | |
Alpha-2A adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals
Curated by ChEMBL
| Assay Description Effective concentration at Alpha-2A adrenergic receptor from CHO-C10 cells |
J Med Chem 40: 18-23 (1997)
Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
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| Article PubMed
| n/a | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a |
Allergan Pharmaceuticals
Curated by ChEMBL
| Assay Description Effective concentration at Alpha-2C adrenergic receptor from CHO-C4 cells |
J Med Chem 40: 18-23 (1997)
Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST |
More data for this Ligand-Target Pair | |
MPI protein
(Homo sapiens (Human)) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | Reactome pathway KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2CF9NFM |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Rattus norvegicus) | BDBM34572
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
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| PCBioAssay
| n/a | n/a | n/a | n/a | 0.0372 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters
Curated by PubChem BioAssay
| Assay Description Assay Provider: Colleen Niswender Assay Provider Affliation: Vanderbilt University Grant Title: Measurement of GPCR-mediated thallium flux through GI... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q21G0JR7 |
More data for this Ligand-Target Pair | |