BindingDB logo
myBDB logout

null

SMILES: CN(C)CCN(Cc1ccccc1C(F)(F)F)C(=O)COc1cccc2CCN(CC3CC3)CCc12

InChI Key: InChIKey=MCECIBHEXVUWJX-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 345948   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Atypical chemokine receptor 3


(Homo sapiens (Human))		BDBM345948
PNG
(2-(3-Cyclopropylmethyl-2,3,4,5-tetrahydro-1H-benzo...)
Show SMILES CN(C)CCN(Cc1ccccc1C(F)(F)F)C(=O)COc1cccc2CCN(CC3CC3)CCc12
Show InChI InChI=1S/C28H36F3N3O2/c1-32(2)16-17-34(19-23-6-3-4-8-25(23)28(29,30)31)27(35)20-36-26-9-5-7-22-12-14-33(15-13-24(22)26)18-21-10-11-21/h3-9,21H,10-20H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1n/an/an/an/a



IDORSIA PHARMACEUTICALS LTD.

US Patent


Assay Description
The assay is using the PathHunter CHO-K1 CXCR7 β-arrestin cell line from DiscoverX. The system is based on the Enzyme Fragment Complementation T...

US Patent US10202368 (2019)


BindingDB Entry DOI: 10.7270/Q2ZK5JRJ
More data for this
Ligand-Target Pair