BDBM346014 US10202370, Example 003::{6-Methyl-2-[4-(4- methyl-piperazin-1- ylmethyl)-phenyl]- 3H-benzoimidazol-5- yl}-(4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: CN1CCN(Cc2ccc(cc2)-c2nc3cc(C)c(Nc4nc(cs4)-c4cccnc4)cc3[nH]2)CC1

InChI Key: InChIKey=PCUILLKUFMASCJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346014 (US10202370, Example 003 | {6-Methyl-2-[4-(4- methy...) Show SMILES CN1CCN(Cc2ccc(cc2)-c2nc3cc(C)c(Nc4nc(cs4)-c4cccnc4)cc3[nH]2)CC1 Show InChI InChI=1S/C28H29N7S/c1-19-14-24-25(15-23(19)32-28-33-26(18-36-28)22-4-3-9-29-16-22)31-27(30-24)21-7-5-20(6-8-21)17-35-12-10-34(2)11-13-35/h3-9,14-16,18H,10-13,17H2,1-2H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair