BDBM346025 US10202370, Example 030::[2-(3-Difluoromethyl- phenyl)-6-methyl- 3H-benzoimidazol-5- yl]-(4-pyridin-3-yl- pyrimidin-2-yl)- amine
SMILES: Cc1cc2nc([nH]c2cc1Nc1nccc(n1)-c1cccnc1)-c1cccc(c1)C(F)F
InChI Key: InChIKey=HNTYXDKNLDTEMY-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM346025 (US10202370, Example 030 | [2-(3-Difluoromethyl- ph...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
AB SCIENCE US Patent | Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin... | US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK | |||||||||||
More data for this Ligand-Target Pair |