BDBM346030 US10202370, Example 035::[6-Methyl-2-(3- piperidin-1-ylmethyl- 5-trifluoromethyl- phenyl)-3H- benzoimidazol-5-yl]- (4-pyridin-3-yl- pyrimidin-2-yl)- amine

SMILES: Cc1cc2nc([nH]c2cc1Nc1nccc(n1)-c1cccnc1)-c1cc(CN2CCCCC2)cc(c1)C(F)(F)F

InChI Key: InChIKey=HOYDPYPZIDPXNV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346030 (US10202370, Example 035 | [6-Methyl-2-(3- piperidi...) Show SMILES Cc1cc2nc([nH]c2cc1Nc1nccc(n1)-c1cccnc1)-c1cc(CN2CCCCC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C30H28F3N7/c1-19-12-26-27(16-25(19)39-29-35-9-7-24(38-29)21-6-5-8-34-17-21)37-28(36-26)22-13-20(14-23(15-22)30(31,32)33)18-40-10-3-2-4-11-40/h5-9,12-17H,2-4,10-11,18H2,1H3,(H,36,37)(H,35,38,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair