BDBM346036 US10202370, Example 056::[6-Methyl-2-(4- methyl-3- trifluoromethyl- phenyl)-3H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1ccc(cc1C(F)(F)F)-c1nc2cc(C)c(Nc3nc(cs3)-c3cccnc3)cc2[nH]1

InChI Key: InChIKey=QXZRVVCOGNZJSK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346036 (US10202370, Example 056 | [6-Methyl-2-(4- methyl-3...) Show SMILES Cc1ccc(cc1C(F)(F)F)-c1nc2cc(C)c(Nc3nc(cs3)-c3cccnc3)cc2[nH]1 Show InChI InChI=1S/C24H18F3N5S/c1-13-5-6-15(9-17(13)24(25,26)27)22-29-19-8-14(2)18(10-20(19)30-22)31-23-32-21(12-33-23)16-4-3-7-28-11-16/h3-12H,1-2H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair