BDBM346038 US10202370, Example 058::[2-(3-Fluoro-5- trifluoromethyl- phenyl)-6-methyl- 3H-benzoimidazol-5- yl]-(4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cc(F)cc(c1)C(F)(F)F

InChI Key: InChIKey=QZRDHGWYEGGXEG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346038 (US10202370, Example 058 | [2-(3-Fluoro-5- trifluor...) Show SMILES Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cccnc1)-c1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C23H15F4N5S/c1-12-5-18-19(30-21(29-18)14-6-15(23(25,26)27)8-16(24)7-14)9-17(12)31-22-32-20(11-33-22)13-3-2-4-28-10-13/h2-11H,1H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair