BDBM346040 US10202370, Example 062::[6-Methyl-2-(3- trifluoromethyl- phenyl)-3H- benzoimidazol-5-yl]- (4-pyrimidin-5-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cncnc1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=PRRKHEBXBFHSEI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346040 (US10202370, Example 062 | [6-Methyl-2-(3- trifluor...) Show SMILES Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1cncnc1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C22H15F3N6S/c1-12-5-17-18(29-20(28-17)13-3-2-4-15(6-13)22(23,24)25)7-16(12)30-21-31-19(10-32-21)14-8-26-11-27-9-14/h2-11H,1H3,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair