BindingDB logo
myBDB logout

null

SMILES: Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1ccc(cc1)C#N)-c1cccc(c1)C(F)F

InChI Key: InChIKey=CVTFOAIPNFCOHI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346041   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mast/stem cell growth factor receptor Kit


(Homo sapiens (Human))		BDBM346041
PNG
(4-{2-[2-(3- Difluoromethyl- phenyl)-6-methyl- 3H-b...)
Show SMILES Cc1cc2nc([nH]c2cc1Nc1nc(cs1)-c1ccc(cc1)C#N)-c1cccc(c1)C(F)F
Show InChI InChI=1S/C25H17F2N5S/c1-14-9-20-21(30-24(29-20)18-4-2-3-17(10-18)23(26)27)11-19(14)31-25-32-22(13-33-25)16-7-5-15(12-28)6-8-16/h2-11,13,23H,1H3,(H,29,30)(H,31,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<1.00E+3n/an/an/an/a



AB SCIENCE

US Patent


Assay Description
Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...

US Patent US10202370 (2019)


BindingDB Entry DOI: 10.7270/Q2Q52RRK
More data for this
Ligand-Target Pair