BDBM346047 4-[2-(6-Methyl-2-m- tolyl-3H- benzoimidazol-5- ylamino)-thiazol-4- yl]-benzonitrile::US10202370, Example 074
SMILES: Cc1cccc(c1)-c1nc2cc(C)c(Nc3nc(cs3)-c3ccc(cc3)C#N)cc2[nH]1
InChI Key: InChIKey=QXLAELHFYHJNOE-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM346047 (4-[2-(6-Methyl-2-m- tolyl-3H- benzoimidazol-5- yla...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
AB SCIENCE US Patent | Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin... | US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK | |||||||||||
More data for this Ligand-Target Pair |