BDBM346055 US10202370, Example 085::[1,6-Dimethyl-2-(3- trifluoromethyl- phenyl)-1H- benzoimidazol-5-yl]- (4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1cccnc1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=LYOSEDZXVGYTKI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346055 (US10202370, Example 085 | [1,6-Dimethyl-2-(3- trif...) Show SMILES Cc1cc2n(C)c(nc2cc1Nc1nc(cs1)-c1cccnc1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H18F3N5S/c1-14-9-21-19(29-22(32(21)2)15-5-3-7-17(10-15)24(25,26)27)11-18(14)30-23-31-20(13-33-23)16-6-4-8-28-12-16/h3-13H,1-2H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair