BDBM346061 US10202370, Example 097::[2-(4-Difluoromethyl- phenyl)-6-methyl- 1H-benzoimidazol-5- yl]-(4-pyridin-3-yl- thiazol-2-yl)-amine

SMILES: Cc1cc2[nH]c(nc2cc1Nc1nc(cs1)-c1cccnc1)-c1ccc(cc1)C(F)F

InChI Key: InChIKey=AMPDWLDVLXGHIH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM346061 (US10202370, Example 097 | [2-(4-Difluoromethyl- ph...) Show SMILES Cc1cc2[nH]c(nc2cc1Nc1nc(cs1)-c1cccnc1)-c1ccc(cc1)C(F)F Show InChI InChI=1S/C23H17F2N5S/c1-13-9-18-19(28-22(27-18)15-6-4-14(5-7-15)21(24)25)10-17(13)29-23-30-20(12-31-23)16-3-2-8-26-11-16/h2-12,21H,1H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a
AB SCIENCE US Patent					Assay Description Colorimetric cell proliferation and viability assay (reagent CellTiter-Blue purchased from Promega cat N°G8081) was performed on BaF3 Kit WT cell lin...				US Patent US10202370 (2019) BindingDB Entry DOI: 10.7270/Q2Q52RRK
					More data for this Ligand-Target Pair