BDBM346239 2-[5-fluoro-4-(2-methyl-4-pyridyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 2::US10202375, Example 9
SMILES: Cc1cc(ccn1)-c1c(F)cnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12
InChI Key: InChIKey=NCYOCYHHOAVAGN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein Wnt-3a (Mus musculus) | BDBM346239 (2-[5-fluoro-4-(2-methyl-4-pyridyl)pyrrolo[2,3-b]py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma PLC US Patent | Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T... | US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Mus musculus) | BDBM346239 (2-[5-fluoro-4-(2-methyl-4-pyridyl)pyrrolo[2,3-b]py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma PLC US Patent | Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T... | US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN | |||||||||||
More data for this Ligand-Target Pair |