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SMILES: Cc1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12

InChI Key: InChIKey=SBVQHHGDUMDMGR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 346240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Mus musculus)	BDBM346240 (2-[5-(2-methyl-4-pyridyl)pyrazolo[3,4-b]pyridin-1-...) Show SMILES Cc1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12 Show InChI InChI=1S/C23H18N8O/c1-15-10-16(4-6-25-15)22-18-5-9-31(23(18)29-14-28-22)13-21(32)30-20-3-2-17(11-27-20)19-12-24-7-8-26-19/h2-12,14H,13H2,1H3,(H,27,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair
Protein Wnt-3a (Mus musculus)	BDBM346240 (2-[5-(2-methyl-4-pyridyl)pyrazolo[3,4-b]pyridin-1-...) Show SMILES Cc1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12 Show InChI InChI=1S/C23H18N8O/c1-15-10-16(4-6-25-15)22-18-5-9-31(23(18)29-14-28-22)13-21(32)30-20-3-2-17(11-27-20)19-12-24-7-8-26-19/h2-12,14H,13H2,1H3,(H,27,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair
Protein Wnt-3a (Mus musculus)	BDBM346240 (2-[5-(2-methyl-4-pyridyl)pyrazolo[3,4-b]pyridin-1-...) Show SMILES Cc1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(cn3)-c3cnccn3)ccc12 Show InChI InChI=1S/C23H18N8O/c1-15-10-16(4-6-25-15)22-18-5-9-31(23(18)29-14-28-22)13-21(32)30-20-3-2-17(11-27-20)19-12-24-7-8-26-19/h2-12,14H,13H2,1H3,(H,27,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair