BDBM346242 2-[5-(2-methyl-4-pyridyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 17::US10202375, Example 5

SMILES: Cc1cc(ccn1)-c1ccnc2n(CC(=O)Nc3ccc(nc3)-c3cnccn3)ccc12

InChI Key: InChIKey=UUAMTKNDYTWEHM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Mus musculus)	BDBM346242 (2-[5-(2-methyl-4-pyridyl)pyrrolo[2,3-b]pyridin-1-y...) Show SMILES Cc1cc(ccn1)-c1ccnc2n(CC(=O)Nc3ccc(nc3)-c3cnccn3)ccc12 Show InChI InChI=1S/C24H19N7O/c1-16-12-17(4-7-26-16)19-5-8-28-24-20(19)6-11-31(24)15-23(32)30-18-2-3-21(29-13-18)22-14-25-9-10-27-22/h2-14H,15H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair
Protein Wnt-3a (Mus musculus)	BDBM346242 (2-[5-(2-methyl-4-pyridyl)pyrrolo[2,3-b]pyridin-1-y...) Show SMILES Cc1cc(ccn1)-c1ccnc2n(CC(=O)Nc3ccc(nc3)-c3cnccn3)ccc12 Show InChI InChI=1S/C24H19N7O/c1-16-12-17(4-7-26-16)19-5-8-28-24-20(19)6-11-31(24)15-23(32)30-18-2-3-21(29-13-18)22-14-25-9-10-27-22/h2-14H,15H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair