BDBM346251 2-[4-(2-methyl-4-pyridyl)pyrazolo[3,4-d]pyrimidin-1-yl]-N-(6-pyrazin-2-yl-3-pyridyl)acetamide::US10202375, Example 14
SMILES: Cc1cc(ccn1)-c1ncnc2n(CC(=O)Nc3ccc(nc3)-c3cnccn3)ncc12
InChI Key: InChIKey=WGXNXYJXCCODQX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein Wnt-3a (Mus musculus) | BDBM346251 (2-[4-(2-methyl-4-pyridyl)pyrazolo[3,4-d]pyrimidin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Redx Pharma PLC US Patent | Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T... | US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN | |||||||||||
More data for this Ligand-Target Pair |