BDBM346252 2-[4-(2-methyl-4-pyridyl)pyrazolo[3,4-b]pyridin-1-yl]-N-(6-pyrazin-2-yl-3-pyridyl)acetamide::US10202375, Example 15

SMILES: Cc1cc(ccn1)-c1ccnc2n(CC(=O)Nc3ccc(nc3)-c3cnccn3)ncc12

InChI Key: InChIKey=AWAFWQFZKAPHOF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Mus musculus)	BDBM346252 (2-[4-(2-methyl-4-pyridyl)pyrazolo[3,4-b]pyridin-1-...) Show SMILES Cc1cc(ccn1)-c1ccnc2n(CC(=O)Nc3ccc(nc3)-c3cnccn3)ncc12 Show InChI InChI=1S/C23H18N8O/c1-15-10-16(4-6-25-15)18-5-7-27-23-19(18)12-29-31(23)14-22(32)30-17-2-3-20(28-11-17)21-13-24-8-9-26-21/h2-13H,14H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair