BDBM346267 2-[4-(1-piperidyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5-pyrazin-2-yl-2-pyridyl)acetamide::US10202375, Example 30

SMILES: O=C(Cn1ccc2c(ccnc12)N1CCCCC1)Nc1ccc(cn1)-c1cnccn1

InChI Key: InChIKey=VXHCZGJHBAZOKW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 346267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Mus musculus)	BDBM346267 (2-[4-(1-piperidyl)pyrrolo[2,3-b]pyridin-1-yl]-N-(5...) Show SMILES O=C(Cn1ccc2c(ccnc12)N1CCCCC1)Nc1ccc(cn1)-c1cnccn1 Show InChI InChI=1S/C23H23N7O/c31-22(28-21-5-4-17(14-27-21)19-15-24-9-10-25-19)16-30-13-7-18-20(6-8-26-23(18)30)29-11-2-1-3-12-29/h4-10,13-15H,1-3,11-12,16H2,(H,27,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description Mouse L cells transfected to constitutively produce biologically active murine Wnt-3a, referred to as L-Wnt cells, were purchased from the American T...				US Patent US10202375 (2019) BindingDB Entry DOI: 10.7270/Q29W0HMN
					More data for this Ligand-Target Pair