Found 37 hits for monomerid = 34651 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sigma non-opioid intracellular receptor 1
(RAT) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 81: 4983-7 (1984)
Article DOI: 10.1073/pnas.81.15.4983 BindingDB Entry DOI: 10.7270/Q2JM284N |
More data for this Ligand-Target Pair | |
Aurora B/Incenp
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| 5.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description Inhibition of human full length N-terminal GST-tagged Aurora B (1 to 344 end residues)/His-tagged INCENP (803 to 918 end residues) expressed in bacul... |
Bioorg Med Chem 26: 3021-3029 (2018)
Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt
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Patents
| Article PubMed
| 8.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description Inhibition of full length human Mps1 using fluorescence-labeled H236 peptide as substrate after 60 to 90 mins in presence of ATP by fluorescence assa... |
Bioorg Med Chem 26: 3021-3029 (2018)
Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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Patents
| Article PubMed
| 3.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Institute of Cancer Research
Curated by ChEMBL
| Assay Description Inhibition of full length N-terminal His-tagged Aurora A (unknown origin) using fluorescence-labeled FL-Peptide 21 as substrate after 60 mins in pres... |
Bioorg Med Chem 26: 3021-3029 (2018)
Article DOI: 10.1016/j.bmc.2018.04.033 BindingDB Entry DOI: 10.7270/Q2736TKN |
More data for this Ligand-Target Pair | |
Homo sapiens phosphodiesterase 2A (PDE2A)
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
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Patents
| PubMed
| n/a | n/a | 7.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of guinea pig ventricle |
J Med Chem 28: 537-45 (1985)
BindingDB Entry DOI: 10.7270/Q2N58MXT |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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Patents
| PubMed
| n/a | n/a | >1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute
Curated by ChEMBL
| Assay Description Inhibition of canine kidney Phosphodiesterase 4 at 0.5 uM |
J Med Chem 33: 317-27 (1990)
BindingDB Entry DOI: 10.7270/Q27S7R0G |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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Patents
| PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute
Curated by ChEMBL
| Assay Description Inhibition of canine heart Phosphodiesterase 4 |
J Med Chem 33: 317-27 (1990)
BindingDB Entry DOI: 10.7270/Q27S7R0G |
More data for this Ligand-Target Pair | |
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
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Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibitory concentration against cGMP PDE II enzyme in guinea pig |
J Med Chem 30: 1955-62 (1987)
BindingDB Entry DOI: 10.7270/Q27S7MS4 |
More data for this Ligand-Target Pair | |
Homo sapiens phosphodiesterase 2A (PDE2A)
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
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Patents
| PubMed
| n/a | n/a | 7.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibitory concentration against cAMP PDE II enzyme in guinea pig |
J Med Chem 30: 1955-62 (1987)
BindingDB Entry DOI: 10.7270/Q27S7MS4 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibitory concentration against cGMP PDE I enzyme in guinea pig |
J Med Chem 30: 1955-62 (1987)
BindingDB Entry DOI: 10.7270/Q27S7MS4 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibitory concentration against cAMP PDE III enzyme in guinea pig |
J Med Chem 30: 1955-62 (1987)
BindingDB Entry DOI: 10.7270/Q27S7MS4 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition of cAMP PDE II enzyme |
J Med Chem 30: 1963-72 (1987)
BindingDB Entry DOI: 10.7270/Q28K79P9 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition of cAMP PDE I enzyme |
J Med Chem 30: 1963-72 (1987)
BindingDB Entry DOI: 10.7270/Q28K79P9 |
More data for this Ligand-Target Pair | |
Homo sapiens phosphodiesterase 2A (PDE2A)
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
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Patents
| PubMed
| n/a | n/a | 5.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition of cGMP PDE II enzyme |
J Med Chem 30: 1963-72 (1987)
BindingDB Entry DOI: 10.7270/Q28K79P9 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition cGMP PDE I enzyme |
J Med Chem 30: 1963-72 (1987)
BindingDB Entry DOI: 10.7270/Q28K79P9 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition of Phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 M |
J Med Chem 32: 342-50 (1989)
BindingDB Entry DOI: 10.7270/Q27083P1 |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricle |
J Med Chem 28: 537-45 (1985)
BindingDB Entry DOI: 10.7270/Q2N58MXT |
More data for this Ligand-Target Pair | |
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricle |
J Med Chem 28: 537-45 (1985)
BindingDB Entry DOI: 10.7270/Q2N58MXT |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.26E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Navarra
Curated by ChEMBL
| Assay Description Inhibition of canine heart phosphodiesterase 4 |
J Med Chem 34: 3023-9 (1991)
BindingDB Entry DOI: 10.7270/Q28K7CBN |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose |
J Med Chem 30: 1421-6 (1987)
BindingDB Entry DOI: 10.7270/Q21J9D0T |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Cardiotonic effect by inhibition of cAMP phosphodiesterase (PDE III) |
J Med Chem 29: 635-40 (1986)
BindingDB Entry DOI: 10.7270/Q2T72KNS |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibition of fraction III of guinea pig phosphodiesterase |
J Med Chem 27: 1099-101 (1984)
BindingDB Entry DOI: 10.7270/Q26Q1W70 |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
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Patents
| Article PubMed
| n/a | n/a | >1.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t... |
Toxicol Sci 118: 485-500 (2010)
Article DOI: 10.1093/toxsci/kfq269 BindingDB Entry DOI: 10.7270/Q26Q20JN |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.71E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... |
Drug Metab Dispos 40: 2332-41 (2012)
Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M |
More data for this Ligand-Target Pair | |
Canalicular multispecific organic anion transporter 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... |
Toxicol Sci 136: 216-41 (2013)
BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Canalicular multispecific organic anion transporter 2
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ... |
Toxicol Sci 136: 216-41 (2013)
BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Multidrug resistance-associated protein 4
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... |
Toxicol Sci 136: 216-41 (2013)
BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc
Curated by ChEMBL
| Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ... |
Toxicol Sci 136: 216-41 (2013)
BindingDB Entry DOI: 10.7270/Q2JM2D2D |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibitory activity against Phosphodiesterase 3 from heart. |
J Med Chem 40: 3248-53 (1997)
Article DOI: 10.1021/jm970089s BindingDB Entry DOI: 10.7270/Q2K93B7D |
More data for this Ligand-Target Pair | |
Phosphodiesterase 1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibitory activity against PDE1 from cerebral cortex |
J Med Chem 40: 3248-53 (1997)
Article DOI: 10.1021/jm970089s BindingDB Entry DOI: 10.7270/Q2K93B7D |
More data for this Ligand-Target Pair | |
Phosphodiesterase 4
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokuriku University
Curated by ChEMBL
| Assay Description Inhibitory activity against Phosphodiesterase 4 from heart. |
J Med Chem 40: 3248-53 (1997)
Article DOI: 10.1021/jm970089s BindingDB Entry DOI: 10.7270/Q2K93B7D |
More data for this Ligand-Target Pair | |
Phosphodiesterase 3
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sterling Winthrop Pharmaceuticals Research Division
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against cAMP phosphodiesterase III in dog aorta |
J Med Chem 37: 248-54 (1994)
Article DOI: 10.1021/jm00028a007 BindingDB Entry DOI: 10.7270/Q2X069RV |
More data for this Ligand-Target Pair | |
Homo sapiens phosphodiesterase 2A (PDE2A)
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 7.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibition of cGMP PDE II enzyme |
J Med Chem 30: 1963-72 (1987)
BindingDB Entry DOI: 10.7270/Q28K79P9 |
More data for this Ligand-Target Pair | |
Homo sapiens phosphodiesterase 2A (PDE2A)
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 5.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company
Curated by ChEMBL
| Assay Description Inhibitory concentration against cAMP PDE II enzyme in guinea pig |
J Med Chem 30: 1955-62 (1987)
BindingDB Entry DOI: 10.7270/Q27S7MS4 |
More data for this Ligand-Target Pair | |
perilipin-5
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PCBioAssay
| n/a | n/a | 7.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2D21W3H |
More data for this Ligand-Target Pair | |
MPI protein
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PCBioAssay
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description The purpose of this assay is to identify non-competititve inhibitors of human PMI. This is accomplished by using a G6PD- NADPH-coupled assay. In the ... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2CF9NFM |
More data for this Ligand-Target Pair | |
perilipin-1
(Homo sapiens (Human)) | BDBM34651
(Amrinon | Amrinone | CHEMBL12856 | Cordemcura | IN...)Show InChI InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG PC cid PC sid UniChem
Patents
| PCBioAssay
| n/a | n/a | >7.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2HT2MS2 |
More data for this Ligand-Target Pair | |