BDBM346730 US10202379, Reference Example 333

SMILES: COCCN1CN(C2c3ccccc3CSc3ccc(Cl)cc23)n2ccc(=O)c(O)c2C1=O

InChI Key: InChIKey=ZGBBRZIQRRZHFG-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346730 (US10202379, Reference Example 333) Show SMILES COCCN1CN(C2c3ccccc3CSc3ccc(Cl)cc23)n2ccc(=O)c(O)c2C1=O Show InChI InChI=1S/C24H22ClN3O4S/c1-32-11-10-26-14-28(27-9-8-19(29)23(30)22(27)24(26)31)21-17-5-3-2-4-15(17)13-33-20-7-6-16(25)12-18(20)21/h2-9,12,21,30H,10-11,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	425	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346730 (US10202379, Reference Example 333) Show SMILES COCCN1CN(C2c3ccccc3CSc3ccc(Cl)cc23)n2ccc(=O)c(O)c2C1=O Show InChI InChI=1S/C24H22ClN3O4S/c1-32-11-10-26-14-28(27-9-8-19(29)23(30)22(27)24(26)31)21-17-5-3-2-4-15(17)13-33-20-7-6-16(25)12-18(20)21/h2-9,12,21,30H,10-11,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair