BDBM346738 US10202379, Reference Example 341

SMILES: Oc1c2C(=O)N(CN(C3c4ccccc4CSc4c(Cl)cccc34)n2ccc1=O)C1CC1

InChI Key: InChIKey=DKADDKDLCZNCNT-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346738 (US10202379, Reference Example 341) Show SMILES Oc1c2C(=O)N(CN(C3c4ccccc4CSc4c(Cl)cccc34)n2ccc1=O)C1CC1 Show InChI InChI=1S/C24H20ClN3O3S/c25-18-7-3-6-17-20(16-5-2-1-4-14(16)12-32-23(17)18)28-13-26(15-8-9-15)24(31)21-22(30)19(29)10-11-27(21)28/h1-7,10-11,15,20,30H,8-9,12-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346738 (US10202379, Reference Example 341) Show SMILES Oc1c2C(=O)N(CN(C3c4ccccc4CSc4c(Cl)cccc34)n2ccc1=O)C1CC1 Show InChI InChI=1S/C24H20ClN3O3S/c25-18-7-3-6-17-20(16-5-2-1-4-14(16)12-32-23(17)18)28-13-26(15-8-9-15)24(31)21-22(30)19(29)10-11-27(21)28/h1-7,10-11,15,20,30H,8-9,12-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair