BDBM346744 US10202379, Reference Example 347

SMILES: CN1CN(C2c3ccccc3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O

InChI Key: InChIKey=KEFIOOTYRGYEAQ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346744 (US10202379, Reference Example 347) Show SMILES CN1CN(C2c3ccccc3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O Show InChI InChI=1S/C22H18ClN3O3S/c1-24-12-26(25-10-9-17(27)20(28)19(25)22(24)29)18-14-6-3-2-5-13(14)11-30-21-15(18)7-4-8-16(21)23/h2-10,18,28H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346744 (US10202379, Reference Example 347) Show SMILES CN1CN(C2c3ccccc3CSc3c(Cl)cccc23)n2ccc(=O)c(O)c2C1=O Show InChI InChI=1S/C22H18ClN3O3S/c1-24-12-26(25-10-9-17(27)20(28)19(25)22(24)29)18-14-6-3-2-5-13(14)11-30-21-15(18)7-4-8-16(21)23/h2-10,18,28H,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair