BDBM346816 US10202379, Reference Example 433

SMILES: C[C@@H](N1CN([C@H]2c3ccc(Br)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=WWJJHERYDQHTPV-XCLFUZPHSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346816 (US10202379, Reference Example 433) Show SMILES C[C@@H](N1CN([C@H]2c3ccc(Br)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C24H19BrF3N3O3S/c1-13(24(26,27)28)29-12-31(30-9-8-18(32)22(33)21(30)23(29)34)20-16-7-6-15(25)10-14(16)11-35-19-5-3-2-4-17(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346816 (US10202379, Reference Example 433) Show SMILES C[C@@H](N1CN([C@H]2c3ccc(Br)cc3CSc3ccccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C24H19BrF3N3O3S/c1-13(24(26,27)28)29-12-31(30-9-8-18(32)22(33)21(30)23(29)34)20-16-7-6-15(25)10-14(16)11-35-19-5-3-2-4-17(19)20/h2-10,13,20,33H,11-12H2,1H3/t13-,20+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair