BDBM346840 US10202379, Reference Example 470

SMILES: C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3c(F)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=HQFAPRGIEIWZHA-BLVKFPJESA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346840 (US10202379, Reference Example 470) Show SMILES C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3c(F)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-18(33)21(34)20(31)23(30)35)19-15-6-5-14(25)9-13(15)10-36-22-16(19)3-2-4-17(22)26/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346840 (US10202379, Reference Example 470) Show SMILES C[C@@H](N1CN([C@H]2c3ccc(F)cc3CSc3c(F)cccc23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C24H18F5N3O3S/c1-12(24(27,28)29)30-11-32(31-8-7-18(33)21(34)20(31)23(30)35)19-15-6-5-14(25)9-13(15)10-36-22-16(19)3-2-4-17(22)26/h2-9,12,19,34H,10-11H2,1H3/t12-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair