BDBM346963 US10202379, Reference Example 665

SMILES: C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=JFZBJSHRRVMFGJ-QVKFZJNVSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346963   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346963 (US10202379, Reference Example 665) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H22F3N3O3S/c1-14-6-5-7-16-12-35-19-9-4-3-8-17(19)21(20(14)16)31-13-29(15(2)25(26,27)28)24(34)22-23(33)18(32)10-11-30(22)31/h3-11,15,21,33H,12-13H2,1-2H3/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346963 (US10202379, Reference Example 665) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3cccc(C)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H22F3N3O3S/c1-14-6-5-7-16-12-35-19-9-4-3-8-17(19)21(20(14)16)31-13-29(15(2)25(26,27)28)24(34)22-23(33)18(32)10-11-30(22)31/h3-11,15,21,33H,12-13H2,1-2H3/t15-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair