BDBM346966 US10202379, Reference Example 682

SMILES: Oc1c2C(=O)N3CCOC[C@@H]3N([C@@H]3c4ccccc4SCc4cccc(Cl)c34)n2ccc1=O

InChI Key: InChIKey=BGILDGMFIVAGHL-PZJWPPBQSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346966 (US10202379, Reference Example 682) Show SMILES Oc1c2C(=O)N3CCOC[C@@H]3N([C@@H]3c4ccccc4SCc4cccc(Cl)c34)n2ccc1=O |r| Show InChI InChI=1S/C24H20ClN3O4S/c25-16-6-3-4-14-13-33-18-7-2-1-5-15(18)21(20(14)16)28-19-12-32-11-10-26(19)24(31)22-23(30)17(29)8-9-27(22)28/h1-9,19,21,30H,10-13H2/t19-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346966 (US10202379, Reference Example 682) Show SMILES Oc1c2C(=O)N3CCOC[C@@H]3N([C@@H]3c4ccccc4SCc4cccc(Cl)c34)n2ccc1=O |r| Show InChI InChI=1S/C24H20ClN3O4S/c25-16-6-3-4-14-13-33-18-7-2-1-5-15(18)21(20(14)16)28-19-12-32-11-10-26(19)24(31)22-23(30)17(29)8-9-27(22)28/h1-9,19,21,30H,10-13H2/t19-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.7	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair