BDBM346967 US10202379, Reference Example 686

SMILES: C[C@@H](N1CN(C2c3ccccc3CCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=MXSKOVOMHZMSAO-CKAQCJTGSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346967 (US10202379, Reference Example 686) Show SMILES C[C@@H](N1CN(C2c3ccccc3CCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H21ClF3N3O3/c1-14(25(27,28)29)30-13-32(31-12-11-19(33)23(34)22(31)24(30)35)21-17-7-3-2-5-15(17)9-10-16-6-4-8-18(26)20(16)21/h2-8,11-12,14,21,34H,9-10,13H2,1H3/t14-,21?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.86	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346967 (US10202379, Reference Example 686) Show SMILES C[C@@H](N1CN(C2c3ccccc3CCc3cccc(Cl)c23)n2ccc(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C25H21ClF3N3O3/c1-14(25(27,28)29)30-13-32(31-12-11-19(33)23(34)22(31)24(30)35)21-17-7-3-2-5-15(17)9-10-16-6-4-8-18(26)20(16)21/h2-8,11-12,14,21,34H,9-10,13H2,1H3/t14-,21?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.1	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair