BDBM346971 US10202379, Reference Example 706

SMILES: C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(C(C)=O)c(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=UBFFCZNPHSGXJF-ASSNKEHSSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346971 (US10202379, Reference Example 706) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(C(C)=O)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C26H20F5N3O4S/c1-12(35)16-9-33-22(24(37)23(16)36)25(38)32(13(2)26(29,30)31)11-34(33)21-14-7-8-18(27)20(28)17(14)10-39-19-6-4-3-5-15(19)21/h3-9,13,21,37H,10-11H2,1-2H3/t13-,21+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.19	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346971 (US10202379, Reference Example 706) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(C(C)=O)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C26H20F5N3O4S/c1-12(35)16-9-33-22(24(37)23(16)36)25(38)32(13(2)26(29,30)31)11-34(33)21-14-7-8-18(27)20(28)17(14)10-39-19-6-4-3-5-15(19)21/h3-9,13,21,37H,10-11H2,1-2H3/t13-,21+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.6	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair