BDBM346975 US10202379, Reference Example 710

SMILES: CC(O)c1cn2N(CN([C@H](C)C(F)(F)F)C(=O)c2c(O)c1=O)[C@@H]1c2ccccc2SCc2cccc(Cl)c12

InChI Key: InChIKey=JYEYWCHTHQTCOB-SGTNWVKBSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346975 (US10202379, Reference Example 710) Show SMILES CC(O)c1cn2N(CN([C@H](C)C(F)(F)F)C(=O)c2c(O)c1=O)[C@@H]1c2ccccc2SCc2cccc(Cl)c12 |r,w:1.1| Show InChI InChI=1S/C26H23ClF3N3O4S/c1-13(34)17-10-32-22(24(36)23(17)35)25(37)31(14(2)26(28,29)30)12-33(32)21-16-7-3-4-9-19(16)38-11-15-6-5-8-18(27)20(15)21/h3-10,13-14,21,34,36H,11-12H2,1-2H3/t13?,14-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.81	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346975 (US10202379, Reference Example 710) Show SMILES CC(O)c1cn2N(CN([C@H](C)C(F)(F)F)C(=O)c2c(O)c1=O)[C@@H]1c2ccccc2SCc2cccc(Cl)c12 |r,w:1.1| Show InChI InChI=1S/C26H23ClF3N3O4S/c1-13(34)17-10-32-22(24(36)23(17)35)25(37)31(14(2)26(28,29)30)12-33(32)21-16-7-3-4-9-19(16)38-11-15-6-5-8-18(27)20(15)21/h3-10,13-14,21,34,36H,11-12H2,1-2H3/t13?,14-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair