BDBM346978 US10202379, Reference Example 716

SMILES: C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(Cl)c(=O)c(O)c2C1=O)C(F)(F)F

InChI Key: InChIKey=XKOWXLNHOMKRPM-WYRIXSBYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346978 (US10202379, Reference Example 716) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(Cl)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C24H17ClF5N3O3S/c1-11(24(28,29)30)31-10-33(32-8-15(25)21(34)22(35)20(32)23(31)36)19-12-6-7-16(26)18(27)14(12)9-37-17-5-3-2-4-13(17)19/h2-8,11,19,35H,9-10H2,1H3/t11-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346978 (US10202379, Reference Example 716) Show SMILES C[C@@H](N1CN([C@@H]2c3ccccc3SCc3c(F)c(F)ccc23)n2cc(Cl)c(=O)c(O)c2C1=O)C(F)(F)F |r| Show InChI InChI=1S/C24H17ClF5N3O3S/c1-11(24(28,29)30)31-10-33(32-8-15(25)21(34)22(35)20(32)23(31)36)19-12-6-7-16(26)18(27)14(12)9-37-17-5-3-2-4-13(17)19/h2-8,11,19,35H,9-10H2,1H3/t11-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.54	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair