BDBM346987 US10202379, Reference Example 731

SMILES: CCc1cccc2CSc3ccccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12

InChI Key: InChIKey=JHGDMHDSXRGIAC-IVZQSRNASA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 346987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346987 (US10202379, Reference Example 731) Show SMILES CCc1cccc2CSc3ccccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12 |r| Show InChI InChI=1S/C26H24F3N3O3S/c1-3-16-7-6-8-17-13-36-20-10-5-4-9-18(20)22(21(16)17)32-14-30(15(2)26(27,28)29)25(35)23-24(34)19(33)11-12-31(23)32/h4-12,15,22,34H,3,13-14H2,1-2H3/t15-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.08	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human))	BDBM346987 (US10202379, Reference Example 731) Show SMILES CCc1cccc2CSc3ccccc3[C@@H](N3CN([C@H](C)C(F)(F)F)C(=O)c4c(O)c(=O)ccn34)c12 |r| Show InChI InChI=1S/C26H24F3N3O3S/c1-3-16-7-6-8-17-13-36-20-10-5-4-9-18(20)22(21(16)17)32-14-30(15(2)26(27,28)29)25(35)23-24(34)19(33)11-12-31(23)32/h4-12,15,22,34H,3,13-14H2,1-2H3/t15-,22-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.76	n/a	n/a	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description A test sample was diluted with a culture medium to an appropriate concentration in advance, and then 2 to 5-fold serial dilution on a 96 well plate (...				US Patent US10202379 (2019) BindingDB Entry DOI: 10.7270/Q2XK8HP2
					More data for this Ligand-Target Pair