BDBM347022 US10202388, Compound 23A-2::US10202388, Compound 26A-3
SMILES: O[C@H](CC1c2c(cccc2F)-c2cncn12)C12CC3CC(C1)[C@H](O)C(C3)C2
InChI Key: InChIKey=SPKRAWSVCLOAAN-UGBJDJEISA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM347022 (US10202388, Compound 23A-2 | US10202388, Compound ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI DE NOVO PHARMATECH CO., LTD. US Patent | Assay Description The compounds described in this disclosure were dissolved in 10% DMSO to predefined concentration. All of the reactions were conducted at room temper... | US Patent US10202388 (2019) BindingDB Entry DOI: 10.7270/Q2JD4ZXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptophan 2,3-dioxygenase (Homo sapiens (Human)) | BDBM347022 (US10202388, Compound 23A-2 | US10202388, Compound ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI DE NOVO PHARMATECH CO., LTD. US Patent | Assay Description The TDO2 enzymatic assay was performed by UV absorption using a recombinant TDO2 and L-Tryptophan substrate. The UV absorption signal at 321 nm is co... | US Patent US10202388 (2019) BindingDB Entry DOI: 10.7270/Q2JD4ZXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM347022 (US10202388, Compound 23A-2 | US10202388, Compound ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI DE NOVO PHARMATECH CO., LTD. US Patent | Assay Description The compounds described in this disclosure were dissolved in 10% DMSO to predefined concentration. All of the reactions were conducted at room temper... | US Patent US10202388 (2019) BindingDB Entry DOI: 10.7270/Q2JD4ZXX | |||||||||||
More data for this Ligand-Target Pair |