BDBM347046 3-(5-(4-(2-hydroxypropan-2-yl)-1H-pyrazol-1-yl)-4-(isopropylamino)pyridin-2-yl) pyrazolo[1,5-a]pyrimidine-6-carbonitrile::US10202390, Example 1

SMILES: CC(C)Nc1cc(ncc1-n1cc(cn1)C(C)(C)O)-c1cnn2cc(cnc12)C#N

InChI Key: InChIKey=QSRKCOCAYVQGSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347046 (3-(5-(4-(2-hydroxypropan-2-yl)-1H-pyrazol-1-yl)-4-...) Show SMILES CC(C)Nc1cc(ncc1-n1cc(cn1)C(C)(C)O)-c1cnn2cc(cnc12)C#N Show InChI InChI=1S/C21H22N8O/c1-13(2)27-18-5-17(16-9-26-29-11-14(6-22)7-24-20(16)29)23-10-19(18)28-12-15(8-25-28)21(3,4)30/h5,7-13,30H,1-4H3,(H,23,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	578	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair