BDBM347048 US10202390, Example 3

SMILES: CC(C)Nc1cc(ncc1-c1cnn(c1)C1CCOCC1)-c1cnc2cc(cnn12)C#N

InChI Key: InChIKey=VGDZIORKWAXUFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347048 (US10202390, Example 3) Show SMILES CC(C)Nc1cc(ncc1-c1cnn(c1)C1CCOCC1)-c1cnc2cc(cnn12)C#N Show InChI InChI=1S/C23H24N8O/c1-15(2)29-20-8-21(22-13-26-23-7-16(9-24)10-28-31(22)23)25-12-19(20)17-11-27-30(14-17)18-3-5-32-6-4-18/h7-8,10-15,18H,3-6H2,1-2H3,(H,25,29)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair