BDBM347051 US10202390, Example 6

SMILES: CCCn1cc(cn1)-c1cnc(cc1NC(C)C)-c1cnc2cc(cnn12)C#N

InChI Key: InChIKey=TWOADEWSFFZZFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347051 (US10202390, Example 6) Show SMILES CCCn1cc(cn1)-c1cnc(cc1NC(C)C)-c1cnc2cc(cnn12)C#N Show InChI InChI=1S/C21H22N8/c1-4-5-28-13-16(10-25-28)17-11-23-19(7-18(17)27-14(2)3)20-12-24-21-6-15(8-22)9-26-29(20)21/h6-7,9-14H,4-5H2,1-3H3,(H,23,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair