BDBM347055 US10202390, Example 10

SMILES: CCCn1cc(cn1)-c1cnc(cc1Nc1cnn(CC(F)F)c1)-c1cnc2cc(cnn12)C#N

InChI Key: InChIKey=SOVIOGDRQIIPMO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347055 (US10202390, Example 10) Show SMILES CCCn1cc(cn1)-c1cnc(cc1Nc1cnn(CC(F)F)c1)-c1cnc2cc(cnn12)C#N Show InChI InChI=1S/C23H20F2N10/c1-2-3-33-12-16(8-29-33)18-10-27-20(21-11-28-23-4-15(6-26)7-31-35(21)23)5-19(18)32-17-9-30-34(13-17)14-22(24)25/h4-5,7-13,22H,2-3,14H2,1H3,(H,27,32)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair