BDBM347059 US10202390, Example 14

SMILES: CC(C)(O)CCc1cn(nn1)-c1cnc(cc1NC1COC1)-c1cnn2cc(Cl)cnc12

InChI Key: InChIKey=WQSAYCODPMMYLW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347059 (US10202390, Example 14) Show SMILES CC(C)(O)CCc1cn(nn1)-c1cnc(cc1NC1COC1)-c1cnn2cc(Cl)cnc12 Show InChI InChI=1S/C21H23ClN8O2/c1-21(2,31)4-3-14-10-29(28-27-14)19-8-23-17(5-18(19)26-15-11-32-12-15)16-7-25-30-9-13(22)6-24-20(16)30/h5-10,15,31H,3-4,11-12H2,1-2H3,(H,23,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair