BDBM347062 US10202390, Example 17

SMILES: CC(C)Nc1cc(ncc1-c1cn(nn1)C1CN(C1)C(C)=O)-c1cnc2cc(cnn12)C#N

InChI Key: InChIKey=FXJWDSCIKROGLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM347062 (US10202390, Example 17) Show SMILES CC(C)Nc1cc(ncc1-c1cn(nn1)C1CN(C1)C(C)=O)-c1cnc2cc(cnn12)C#N Show InChI InChI=1S/C22H22N10O/c1-13(2)27-18-5-19(21-9-25-22-4-15(6-23)7-26-32(21)22)24-8-17(18)20-12-31(29-28-20)16-10-30(11-16)14(3)33/h4-5,7-9,12-13,16H,10-11H2,1-3H3,(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description TBD				US Patent US10202390 (2019) BindingDB Entry DOI: 10.7270/Q28W3GDC
					More data for this Ligand-Target Pair