BDBM347120 2-(4-((4-isopropylphenyl) (1-methylpyrrolidin-3-yl)amino) phenoxy)pyrido[3,4-d]pyrimidin-4-ol::US10202381, Example 127::US10208039, Example 127

SMILES: CC(C)c1ccc(cc1)N(C1CCN(C)C1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1

InChI Key: InChIKey=RLCRSIGMHROGTK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM347120 (2-(4-((4-isopropylphenyl) (1-methylpyrrolidin-3-yl...) Show SMILES CC(C)c1ccc(cc1)N(C1CCN(C)C1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)19-4-6-20(7-5-19)32(22-13-15-31(3)17-22)21-8-10-23(11-9-21)34-27-29-25-16-28-14-12-24(25)26(33)30-27/h4-12,14,16,18,22H,13,15,17H2,1-3H3,(H,29,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research, Inc. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM347120 (2-(4-((4-isopropylphenyl) (1-methylpyrrolidin-3-yl...) Show SMILES CC(C)c1ccc(cc1)N(C1CCN(C)C1)c1ccc(Oc2nc(O)c3ccncc3n2)cc1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)19-4-6-20(7-5-19)32(22-13-15-31(3)17-22)21-8-10-23(11-9-21)34-27-29-25-16-28-14-12-24(25)26(33)30-27/h4-12,14,16,18,22H,13,15,17H2,1-3H3,(H,29,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
CELGENE QUANTICEL RESEARCH, INC. US Patent					Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ...				US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM
					More data for this Ligand-Target Pair