BDBM347125 2-(4-((3-(4-isopropylpiperazin-1- yl)phenyl)(methyl)amino)phenoxy) pyrido[3,4-d]pyrimidin-4-ol::US10202381, Example 132::US10208039, Example 132
SMILES: CC(C)N1CCN(CC1)c1cccc(c1)N(C)c1ccc(Oc2nc(O)c3ccncc3n2)cc1
InChI Key: InChIKey=PJQNDBNJFCXLPU-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM347125 (2-(4-((3-(4-isopropylpiperazin-1- yl)phenyl)(methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Quanticel Research, Inc. US Patent | Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ... | US Patent US10208039 (2019) BindingDB Entry DOI: 10.7270/Q241706J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysine-specific demethylase 4C (Homo sapiens (Human)) | BDBM347125 (2-(4-((3-(4-isopropylpiperazin-1- yl)phenyl)(methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
CELGENE QUANTICEL RESEARCH, INC. US Patent | Assay Description The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate-format under the following reaction conditions: 0.3 ... | US Patent US10202381 (2019) BindingDB Entry DOI: 10.7270/Q2SX6GBM | |||||||||||
More data for this Ligand-Target Pair |