BDBM347146 US10202404, Compound A-17

SMILES: C[C@@H]1CCO[C@H]2Cn3cc(-c4nnc(Cc5cccc(Cl)c5F)s4)c(=O)c(O)c3C(=O)N12

InChI Key: InChIKey=NXWMGDQSTJADHV-BMIGLBTASA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM347146 (US10202404, Compound A-17) Show SMILES C[C@@H]1CCO[C@H]2Cn3cc(-c4nnc(Cc5cccc(Cl)c5F)s4)c(=O)c(O)c3C(=O)N12 |r| Show InChI InChI=1S/C21H18ClFN4O4S/c1-10-5-6-31-15-9-26-8-12(18(28)19(29)17(26)21(30)27(10)15)20-25-24-14(32-20)7-11-3-2-4-13(22)16(11)23/h2-4,8,10,15,29H,5-7,9H2,1H3/t10-,15+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Previously, a series of two-fold dilution on test samples were carried out in a 96-well plate (50 μL/well). Two plates were made for measuring a...				US Patent US10202404 (2019) BindingDB Entry DOI: 10.7270/Q2WQ05WN
					More data for this Ligand-Target Pair