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SMILES: C[C@H]1CCO[C@@H]2Cn3cc(-c4nnc(Cc5ccc(F)cc5F)s4)c(=O)c(O)c3C(=O)N12

InChI Key: InChIKey=QEFFLWCGYKEFAQ-MGPLVRAMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347158   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM347158
PNG
(US10202404, Compound A-29)
Show SMILES C[C@H]1CCO[C@@H]2Cn3cc(-c4nnc(Cc5ccc(F)cc5F)s4)c(=O)c(O)c3C(=O)N12 |r|
Show InChI InChI=1S/C21H18F2N4O4S/c1-10-4-5-31-16-9-26-8-13(18(28)19(29)17(26)21(30)27(10)16)20-25-24-15(32-20)6-11-2-3-12(22)7-14(11)23/h2-3,7-8,10,16,29H,4-6,9H2,1H3/t10-,16+/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.10n/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Previously, a series of two-fold dilution on test samples were carried out in a 96-well plate (50 μL/well). Two plates were made for measuring a...

US Patent US10202404 (2019)


BindingDB Entry DOI: 10.7270/Q2WQ05WN
More data for this
Ligand-Target Pair