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BDBM347166 US10202404, Compound A-38

SMILES: C[C@@H]1C[C@@H](C)N2[C@H](Cn3cc(-c4nnc(Cc5ccc(F)cc5F)s4)c(=O)c(O)c3C2=O)O1

InChI Key: InChIKey=KSPWLULZPCFFBQ-AGKHESDQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347166   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM347166
PNG
(US10202404, Compound A-38)
Show SMILES C[C@@H]1C[C@@H](C)N2[C@H](Cn3cc(-c4nnc(Cc5ccc(F)cc5F)s4)c(=O)c(O)c3C2=O)O1 |r|
Show InChI InChI=1S/C22H20F2N4O4S/c1-10-5-11(2)32-17-9-27-8-14(19(29)20(30)18(27)22(31)28(10)17)21-26-25-16(33-21)6-12-3-4-13(23)7-15(12)24/h3-4,7-8,10-11,17,30H,5-6,9H2,1-2H3/t10-,11-,17+/m1/s1
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 2.70n/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Previously, a series of two-fold dilution on test samples were carried out in a 96-well plate (50 μL/well). Two plates were made for measuring a...

US Patent US10202404 (2019)


BindingDB Entry DOI: 10.7270/Q2WQ05WN
More data for this
Ligand-Target Pair