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SMILES: Oc1c2C(=O)N3C[C@H]4CCCN4[C@@H]3Cn2cc(-c2nnc(Cc3cccc(Cl)c3F)s2)c1=O

InChI Key: InChIKey=ZQXVRVKDNZIGGR-WBMJQRKESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347181   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM347181
PNG
(US10202404, Compound A-54)
Show SMILES Oc1c2C(=O)N3C[C@H]4CCCN4[C@@H]3Cn2cc(-c2nnc(Cc3cccc(Cl)c3F)s2)c1=O |r|
Show InChI InChI=1S/C22H19ClFN5O3S/c23-14-5-1-3-11(17(14)24)7-15-25-26-21(33-15)13-9-27-10-16-28-6-2-4-12(28)8-29(16)22(32)18(27)20(31)19(13)30/h1,3,5,9,12,16,31H,2,4,6-8,10H2/t12-,16+/m1/s1
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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.60n/an/an/an/a



SHIONOGI & CO., LTD.

US Patent


Assay Description
Previously, a series of two-fold dilution on test samples were carried out in a 96-well plate (50 μL/well). Two plates were made for measuring a...

US Patent US10202404 (2019)


BindingDB Entry DOI: 10.7270/Q2WQ05WN
More data for this
Ligand-Target Pair