BDBM347252 US10202404, Compound C-27

SMILES: COCCN1Cn2cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C(=O)N1CCOC

InChI Key: InChIKey=LMNSFODRYPLWLM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM347252 (US10202404, Compound C-27) Show SMILES COCCN1Cn2cc(-c3nnc(Cc4ccc(F)cc4F)s3)c(=O)c(O)c2C(=O)N1CCOC Show InChI InChI=1S/C22H23F2N5O5S/c1-33-7-5-28-12-27-11-15(19(30)20(31)18(27)22(32)29(28)6-8-34-2)21-26-25-17(35-21)9-13-3-4-14(23)10-16(13)24/h3-4,10-11,31H,5-9,12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
SHIONOGI & CO., LTD. US Patent					Assay Description Previously, a series of two-fold dilution on test samples were carried out in a 96-well plate (50 μL/well). Two plates were made for measuring a...				US Patent US10202404 (2019) BindingDB Entry DOI: 10.7270/Q2WQ05WN
					More data for this Ligand-Target Pair