BDBM347420 US10869871, ID # SW209280::US9789116, SW209280

SMILES: CCCS(=O)c1sc2nc(cc(-c3nccn3C)c2c1N)-c1nccs1

InChI Key: InChIKey=TXODEMBBBRCSQG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 347420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD+] (Homo sapiens (Human))	BDBM347420 (US10869871, ID # SW209280 | US9789116, SW209280) Show SMILES CCCS(=O)c1sc2nc(cc(-c3nccn3C)c2c1N)-c1nccs1 Show InChI InChI=1S/C17H17N5OS3/c1-3-8-26(23)17-13(18)12-10(14-19-4-6-22(14)2)9-11(21-16(12)25-17)15-20-5-7-24-15/h4-7,9H,3,8,18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.73	n/a	n/a	n/a	n/a	n/a	n/a
CASE WESTERN RESERVE UNIVERSITY; THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM US Patent					Assay Description Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...				US Patent US10869871 (2020)
					More data for this Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+] (Homo sapiens (Human))	BDBM347420 (US10869871, ID # SW209280 | US9789116, SW209280) Show SMILES CCCS(=O)c1sc2nc(cc(-c3nccn3C)c2c1N)-c1nccs1 Show InChI InChI=1S/C17H17N5OS3/c1-3-8-26(23)17-13(18)12-10(14-19-4-6-22(14)2)9-11(21-16(12)25-17)15-20-5-7-24-15/h4-7,9H,3,8,18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.73	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University; Board of Regents of the University of Texas System US Patent					Assay Description Each compound for inhibiting enzymatic activity of recombinant 15-PGDH in an in vitro assay.				US Patent US9789116 (2017) BindingDB Entry DOI: 10.7270/Q2VQ34T5
					More data for this Ligand-Target Pair