Found 3 hits for monomerid = 347471 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM347471
(US9790180, ID 005)Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C28H34N6O2S/c1-32-14-16-34(17-15-32)28(36)33-12-10-23(11-13-33)30-22-7-4-20(5-8-22)27(35)31-25-19-21(6-9-24(25)29)26-3-2-18-37-26/h2-9,18-19,23,30H,10-17,29H2,1H3,(H,31,35) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
REGENACY PHARMACEUTICALS, LLC
US Patent
| Assay Description Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were... |
US Patent US9790180 (2017)
BindingDB Entry DOI: 10.7270/Q2GF0WM8 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM347471
(US9790180, ID 005)Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C28H34N6O2S/c1-32-14-16-34(17-15-32)28(36)33-12-10-23(11-13-33)30-22-7-4-20(5-8-22)27(35)31-25-19-21(6-9-24(25)29)26-3-2-18-37-26/h2-9,18-19,23,30H,10-17,29H2,1H3,(H,31,35) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
REGENACY PHARMACEUTICALS, LLC
US Patent
| |
US Patent US9790180 (2017)
BindingDB Entry DOI: 10.7270/Q2GF0WM8 |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM347471
(US9790180, ID 005)Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C28H34N6O2S/c1-32-14-16-34(17-15-32)28(36)33-12-10-23(11-13-33)30-22-7-4-20(5-8-22)27(35)31-25-19-21(6-9-24(25)29)26-3-2-18-37-26/h2-9,18-19,23,30H,10-17,29H2,1H3,(H,31,35) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
REGENACY PHARMACEUTICALS, LLC
US Patent
| |
US Patent US9790180 (2017)
BindingDB Entry DOI: 10.7270/Q2GF0WM8 |
More data for this Ligand-Target Pair | |