BDBM347679 (E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-methoxyphenyl)prop- 2-en-1-one ::US9790217, 4::US9790217, 5

SMILES: COc1ccccc1C(=O)C(\Oc1ccc(Cl)cc1)=C/N(C)C

InChI Key: InChIKey=WYFRALRYKRAZGD-SFQUDFHCSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 347679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM347679 ((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-me...) Show SMILES COc1ccccc1C(=O)C(\Oc1ccc(Cl)cc1)=C/N(C)C Show InChI InChI=1S/C18H18ClNO3/c1-20(2)12-17(23-14-10-8-13(19)9-11-14)18(21)15-6-4-5-7-16(15)22-3/h4-12H,1-3H3/b17-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.000100	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM347679 ((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-me...) Show SMILES COc1ccccc1C(=O)C(\Oc1ccc(Cl)cc1)=C/N(C)C Show InChI InChI=1S/C18H18ClNO3/c1-20(2)12-17(23-14-10-8-13(19)9-11-14)18(21)15-6-4-5-7-16(15)22-3/h4-12H,1-3H3/b17-12+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0120	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM347679 ((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-me...) Show SMILES COc1ccccc1C(=O)C(\Oc1ccc(Cl)cc1)=C/N(C)C Show InChI InChI=1S/C18H18ClNO3/c1-20(2)12-17(23-14-10-8-13(19)9-11-14)18(21)15-6-4-5-7-16(15)22-3/h4-12H,1-3H3/b17-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00300	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM347679 ((E)-2-(4-Chlorophenoxy)-3- (dimethylamino)-1-(2-me...) Show SMILES COc1ccccc1C(=O)C(\Oc1ccc(Cl)cc1)=C/N(C)C Show InChI InChI=1S/C18H18ClNO3/c1-20(2)12-17(23-14-10-8-13(19)9-11-14)18(21)15-6-4-5-7-16(15)22-3/h4-12H,1-3H3/b17-12+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00100	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description G-402 cells can be obtained from ATCC (CRL-1440) and were originally derived from a renal leiomyoblastoma.The expression plasmids contains the ORF fo...				US Patent US9790217 (2017) BindingDB Entry DOI: 10.7270/Q2K64M6M
					More data for this Ligand-Target Pair